Generic Name: magnesium sulfate injection (mag NEE see um SUL fate)
Brand Names: Sulfamag
What is magnesium sulfate injection?
Magnesium is a naturally occurring mineral. Magnesium is important for many systems in the body especially the muscles and nerves.
Magnesium sulfate injection is used to used to control low blood levels of magnesium (hypomagnesemia). Magnesium sulfate injection is also used for pediatric acute nephritis and to prevent seizures in severe pre-eclampsia, eclampsia, or toxemia of pregnancy.
Magnesium sulfate injection may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about magnesium sulfate injection?
Magnesium sulfate injection should be administered as an injection into a muscle or intravenously by a healthcare provider. It should be administered in a clinical setting where an emergency situation can be handled properly.
What should I discuss with my healthcare provider before using magnesium sulfate injection?
Do not use magnesium sulfate injection without first talking to your doctor if you
are dehydrated;
have a stomach or intestinal condition;
- have kidney disease; or
have heart disease.
You may not be able to use magnesium sulfate injection, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
Tell your doctor about all prescription or over-the-counter medicines including vitamins, minerals, and herbal products that your are taking.
Tell your doctor if you drink alcohol or caffeine drinks regularly, if you smoke, or if you use any illegal drugs. These factors can affect the way magnesium sulfate injection works in your body.
Magnesium sulfate injection is in the FDA pregnancy category B. This means that it is not expected to harm an unborn baby. Do not use magnesium sulfate injection without first talking to your doctor if you are pregnant. Do not use magnesium sulfate injection without first talking to your doctor if you are breast-feeding a baby.
How should I use magnesium sulfate injection?
Magnesium sulfate injection should be administered as an injection into a muscle or intravenously by a healthcare provider. It should be administered in a clinical setting where an emergency situation can be handled properly.
Your healthcare provider will store magnesium sulfate injection as directed by the manufacturer.
What happens if I miss a dose?
Since the medication will be administered by a healthcare provider, missing a dose should not occur.
What happens if I overdose?
If an overdose of magnesium sulfate injection is suspected, seek emergency medical attention or contact your healthcare provider immediately.
Magnesium sulfate injection should be administered in a clinical setting where an emergency situation can be handled properly.
What should I avoid while using magnesium sulfate injection?
Tell your doctor if you drink alcohol or caffeine drinks regularly, if you smoke, or if you use any illegal drugs. These factors can affect the way magnesium sulfate injection works in your body.
Magnesium sulfate injection side effects
Side effects with magnesium sulfate injection are not common. Serious side effects include:
an allergic reaction (shortness of breath; closing of the throat; hives; swelling of the lips, face, or tongue; rash; or fainting);
heart disturbances;
breathing difficulties;
poor reflexes;
confusion, extreme tiredness or weakness;
low body temperature;
severe headache;
fainting;
rash or flushing;
vision problems; or
nausea or vomiting.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Magnesium sulfate injection Dosing Information
Usual Adult Dose for Hypomagnesemia:
1 g IM every 6 hours for 4 doses (mild hypomagnesemia) or
as much as 2 mEq/kg (0.5 mL of a 50% solution) within 4 hours if necessary (more severe hypomagnesemia) or
5 g in 1 L IV fluid over 3 hours.
Administration should be discontinued as soon as the desired clinical effect is achieved and the serum level is normal.
Usual Adult Dose for Ventricular Arrhythmia:
Initial dose: 1 to 3 g IV bolus over 2 to 15 minutes.
Most studies have continued infusions for 24 to 48 hours.
A 1 to 3 g bolus may be repeated in 15 minutes.
Thereafter, 1 to 2 g may be administered by continuous IV infusion.
Usual Adult Dose for Seizure Prophylaxis:
Seizure Prevention in Preeclampsia/Eclampsia:
Initial: IM: 4 to 5 g of a 50% solution every 4 hours as necessary.
IV: 4 g of a 10% to 20% solution, not exceeding 1.5 mL/min of a 10% solution.
Maintenance: IV Infusion: 1 to 2 g/hour. Maximum dose should not exceed 30 to 40 g/day.
What other drugs will affect magnesium sulfate injection?
Before taking magnesium sulfate injection, talk to your doctor if you are taking
seizure medications;
medications to help you sleep;
medications for allergies or hay fever;
medications for anxiety, mental problems, or psychotic disturbances;
laxatives or antacids;
dietary supplements; or
medications for pain control.
You not be able to take magnesium sulfate, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.
Other drugs can interact with magnesium sulfate injection resulting in dangerous side effects and/or decreased effectiveness. Do not take any other prescription or over-the-counter medicines, including vitamins, minerals, and herbal products, without first talking to your doctor during treatment with magnesium sulfate injection.
More magnesium sulfate injection resources
- Magnesium sulfate injection Side Effects (in more detail)
- Magnesium sulfate injection Dosage
- Magnesium sulfate injection Use in Pregnancy & Breastfeeding
- Magnesium sulfate injection Drug Interactions
- Magnesium sulfate injection Support Group
- 0 Reviews for Magnesium sulfate - Add your own review/rating
Compare magnesium sulfate injection with other medications
- Hypomagnesemia
- Seizure Prevention
- Ventricular Arrhythmia
Where can I get more information?
- Your pharmacist has additional information about magnesium sulfate injection written for health professionals that you may read.
See also: magnesium sulfate side effects (in more detail)
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